Effective guide on using Ortho Home Defense Insect Killer for indoor and perimeter pest control. Keep your home bug-free safely and easily.
Professional elimination is the ONLY safe and effective solution. DIY methods fail 90% of the time and can make the problem worse.
Average response time
Satisfaction guarantee

Home Defense Insect Killer for Indoor & Perimeter by Ortho

Call now for same-day, eco-friendly pest control
With over 20 years of experience, Anchor Pest offers personalized, chemical-safe quarterly subscriptions, protecting homes and businesses across Manchester and surrounding counties with ongoing peace of mind.
Make sure pets and children are out of the area before you begin. Remove or cover all food, dishes, and utensils, especially if treating the kitchen. If treating along indoor walls, move furniture or items sitting against the walls. Open windows for ventilation if possible. Read all label instructions on the bottle for important safety information.
Professional pest control eliminates troubles immediately. Our safe, effective treatments protect your loved ones from dangerous diseases.

Call now for same-day, eco-friendly pest control
With over 20 years of experience, Anchor Pest offers personalized, chemical-safe quarterly subscriptions, protecting homes and businesses across Manchester and surrounding counties with ongoing peace of mind.
Ortho Home Defense Insect Killer for Indoor & Perimeter is a ready-to-use chemical spray designed specifically to control and eliminate a wide variety of common household insects both inside your home and around its edges (the perimeter). It targets pests like ants, roaches, spiders, and other crawling insects that are often found in kitchens, bathrooms, basements, garages, and the areas immediately outside doors, windows, and your home's foundation. This product is formulated to create a protective barrier that both kills insects on contact and keeps them from coming back for a set period of time.
Ortho Home Defense Insect Killer contains active chemical ingredients—most commonly bifenthrin and zeta-cypermethrin. These are synthetic pyrethroids, which are man-made versions of natural insect-killing substances found in chrysanthemum flowers. When insects come into contact with treated surfaces, these chemicals disrupt their nervous systems, causing paralysis and eventually killing them. The formula is water-based, which means it does not leave behind oily residues or stains when used as directed.
This product is specifically labeled for use:
Ortho Home Defense Insect Killer is formulated to control a range of household pests, including:
The main goal of Ortho Home Defense Insect Killer is to help homeowners maintain a pest-free environment by creating an invisible, odorless barrier that kills insects quickly and keeps new pests from entering for weeks or even months, depending on surface type and level of infestation. It is designed for convenience—most versions come in an easy-to-use spray bottle or with a battery-operated wand for large areas.
When used according to the product label, Ortho Home Defense Insect Killer is generally considered safe for use in homes with children and pets, as it dries quickly and does not have a lingering smell. However, it should only be applied to surfaces as specified and should not be sprayed directly on people, pets, or food preparation surfaces.
Start by thoroughly cleaning the area with a disinfectant to kill germs left by mice. Pay attention to high-touch surfaces to prevent infection. This page also details safe cleaning practices.
Read MoreLorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.
Block quote
Ordered list
Unordered list
Bold text
Emphasis
Superscript
Subscript
Discover effective steps to prevent rats from coming back to your home. Learn practical tips for long-term rodent control and a rat-free environment.
Read MoreLorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.
Block quote
Ordered list
Unordered list
Bold text
Emphasis
Superscript
Subscript
Identify if you have mice or rats by inspecting droppings and nests. Mice leave small, pellet-like droppings, while rat droppings are larger and more cylindrical. The page also outlines specific behaviors and other key identification tips.
Read MoreLorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.
Block quote
Ordered list
Unordered list
Bold text
Emphasis
Superscript
Subscript
Discover the pros and cons of using poison to kill mice. Learn safer, more effective alternatives for rodent control in your home.
Read MoreLorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.
Block quote
Ordered list
Unordered list
Bold text
Emphasis
Superscript
Subscript
No, bleach is not recommended for cleaning rodent droppings due to its ineffectiveness. Instead, use a disinfectant specifically designed for hazardous waste. This page also discusses proper cleanup techniques to ensure safety.
Read MoreLorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.
Block quote
Ordered list
Unordered list
Bold text
Emphasis
Superscript
Subscript
Professionals remove rat infestations primarily through thorough inspections and sealing entry points. Watch for signs like droppings and gnaw marks. The page also covers trapping methods and safe removal techniques.
Read MoreLorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.
Block quote
Ordered list
Unordered list
Bold text
Emphasis
Superscript
Subscript
Our certified technicians eliminate pests infestations completely and permanently.
Here's what you get:
🔍
Trained experts identify entry points and nesting areas
🛡️
Pet and family-friendly methods used
🎯
Targets entire colony, not just visible insects or rodents
📋
Long-term exclusion strategies
🧽
Proper cleanup and sanitization
✅
Service warranty and follow-up visits
Complete property assessment within 24 hours
Safe, effective treatment of entire colony
Long-term exclusion and monitoring
Join thousands of satisfied customers who chose professional pest control.
100% satisfaction guarantee.
Quarterly Subscription Plans • Licensed & Insured • Same-Day Start • 100% Satisfaction Guarantee